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Wiley, Angewandte Chemie International Edition, 31(48), p. 5691-5693, 2009

DOI: 10.1002/anie.200902236

Wiley, Angewandte Chemie, 31(121), p. 5801-5803, 2009

DOI: 10.1002/ange.200902236

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Copper-Catalyzed Cross-Couplings with Part-per-Million Catalyst Loadings

This paper is available in a repository.
This paper is available in a repository.

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Abstract

Homeopathic doses: The presence of 0.001 mol % of a copper salt can be sufficient to catalyze arylation reactions of various nucleophiles with phenyl iodide. The two most important factors governing the reaction outcome are the ligand quantity and the temperature.