A new type of optical probe based on laser Doppler self-mixing technology, for a truly non-contact measurement in a single location, and extraction of the temporal features of the distension wave in the arterial wall, was developed. The monitoring of temporal features allows the assessment of cardiovascular function when measurement is carried out at the carotid artery. An algorithm based on the short-time Fourier transform and empirical mode decomposition was applied to the test setup self-mixing signals for the determination of waveform features, with an accuracy of a few milliseconds and a root mean square error less than 3 ms. In vivo testing signals show great consistency in the measured pulse pressure waveform.