Permanent denervated muscles were evaluated by ultra sound (US) to monitor changes in morphology, thickness, contraction-relaxation kinetics and perfusion. In a case of monolateral lesion of the sciatic nerve (due to a surgical neurotomy during the removal of hyperplastic lifenodes in the pelvis) morphology and ultrasonographic structure of the denervated muscles changed during a period of electro stimulation from a pattern typical of complete denervation-induced muscle atrophy to a pattern which might be considered "normal" when detected in an old patient. Despite the higher than normal energy of the delivered electrical stimuli of Vienna home-based Functional Electrical Stimulation (h-b FES) the muscles shown electromyografic and ultrasonographyc signs of re-innervation during the years of training.