Published in

Taylor and Francis Group, Journal of Extracellular Vesicles, 1(2), p. 20304, 2013

DOI: 10.3402/jev.v2i0.20304

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Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress

Journal article published in 2013 by Paulina Kucharzewska, Mattias Belting ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Cells are constantly subjected to various types of endogenous and exogenous stressful stimuli, which can cause serious and even permanent damage. The ability of a cell to sense and adapt to environmental alterations is thus vital to maintain tissue homeostasis during development and adult life. Here, we review some of the major phenotypic characteristics of the hostile tumour microenvironment and the emerging roles of extracellular vesicles in these events.