This article presents the development of a prototype insole derived from natural rubber from Hevea brasiliensis, equipped with pressure control and capable of neoformation of tissue for people who have diabetic foot. The active element of this insole is the electronic circuit that monitors the plantar pressure. In addition, on the present stage of the research, a signal irradiating cell is used based on the principle of tissue regeneration using laser. This project proposes a "smart" insole prototype with a pressure monitoring system and an electronic system for tissue regeneration, which will open a new approach in an attempt to solve the problem of diabetic foot.