Necrotizing sialometaplasia is an uncommon inflammatory condition that affects salivary glands. A 38-year-old man with bilateral ulcerative painful lesions at the junction of the hard and soft palate was presented. An incisional biopsy was performed. Histopathologically, pseudoepithelomatous hyperplasia, lobular necrosis with through the maintenance of the architecture of salivary glands and squamous metaplasia of residual acinar and ductal elements with a bland appearance were observed. The complete self-healing of the lesions occurred in 3 weeks. Since this entity presents clinical and histopathological findings resembling either mucoepidermoid carcinoma or squamous carcinoma diagnostic failure may culminate in unnecessary mutilating surgery.