Macronutrients, photosynthetic pigments, and particle export were assessed in two eddies during the E-Flux I and III cruises to investigate linkages between biogeochemical properties and export flux in Hawaiian lee cyclonic eddies. Cyclone Noah (E-Flux I), speculated to be in the ‘decay’ stage, exhibited modest increases in macronutrients and photosynthetic pigments at the eddy center compared to ambient waters. Cyclone Opal (E-Flux III) also exhibited modest increases in macronutrient concentrations, but a 2-fold enhancement in total chlorophyll a (TChl a) concentration within the eddy center. As indicated by fucoxanthin concentrations, the phytoplankton community in the deep chlorophyll maximum (DCM) of Opal was comprised mainly of diatoms. During an 8-day time series in the center of Opal, TChl a concentration and fucoxanthin in the DCM decreased by ∼50%, which was potentially triggered by silicic acid limitation. Despite the presence of a substantial diatom bloom, Opal did not deliver the expected export of particulate carbon and nitrogen, but rather a large biogenic silica export (∼4-fold increase relative to export in surrounding waters). Results suggest that controls on the life cycle of a Hawaiian lee cyclone are likely a combination of physical (eddy dynamics), chemical (nutrient limitation), and biological (growth and grazing imbalance) processes. Comparisons between Noah and Opal and previously studied cyclones in the region point to a relationship between the spin-up duration of a cyclone and the resulting biological response. Nonetheless, Hawaiian lee cyclones, which strongly influence the biogeochemistry of areas 100's of km in scale in the subtropical North Pacific Ocean, still remain an enigma.