Published in
American Society for Microbiology, Antimicrobial Agents and Chemotherapy, 6(53), p. 2643-2645, 2009
DOI: 10.1128/aac.01534-08
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Prevalence of aac(6')-Ib-cr Encoding a Ciprofloxacin-Modifying Enzyme among Enterobacteriaceae Blood Isolates in Korea
,
Sang-Oh Lee,
Mi-Na Kim,
Jun Hee Woo,
Yang Soo Kim
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Abstract
The aac(6′)-Ib gene was detected in 86 of 555 (15.5%) Enterobacteriaceae isolates. Among these 86 aac(6′)-Ib-positive isolates, 19 (22.0%) were positive for aac(6′)-Ib-cr: 4 of 31 (12.9%) Enterobacter spp., 7 of 13 (53.8%) Escherichia coli isolates, and 8 of 42 (19.0%) Klebsiella pneumoniae isolates. There was a strong association between aac(6′)-Ib-cr and OXA-1 and CTX-M-1 group β-lactamase genes. One aac(6′)-Ib- positive K. pneumoniae isolate carried both aac(6′)-Ib-cr and qnrS. Copyright © 2009, American Society for Microbiology. All Rights Reserved.