Published in
Elsevier, Journal of the Neurological Sciences, 1-2(341), p. 165-166, 2014
DOI: 10.1016/j.jns.2014.04.013
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Opsoclonus–myoclonus syndrome associated with human herpes virus-6 rhomboencephalitis
,
Domenico Santoro,
Monica Rezzonico,
Marco Arnaboldi
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Abstract
Opsoclonus-myoclonus syndrome (OMS) is characterized by opsoclonus and arrhythmic-action myoclonus that predominantly involves the trunk, limbs, and head. Human herpes virus-6 (HHV-6) can rarely cause encephalitis in immunocompetent children and adults. Here we report on a case of OMS associated with HHV-6 rhomboencephalitis. HHV-6 infection should be considered in OMS adults and detection of cell-free viral DNA, indicative of active infection, is mandatory in such cases.