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Bohn Stafleu van Loghum, Critical Care, 6(15), p. 1009

DOI: 10.1186/cc10527

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Finding new therapies for sepsis: the need for patient stratification and the use of genetic biomarkers

Journal article published in 2011 by Michael J. Hobson, Hector R. Wong ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Abstract Reversing the immunoparalysis associated with septic shock remains a priority for improving the outcome of patients suffering from sepsis. The efficacy of future therapies may be better studied under an effective system of patient stratification. Gene expression biomarkers offer a mechanism by which patients may be appropriately stratified in such clinical trials.