Published in
Elsevier, Immunity, 2(33), p. 143-145, 2010
DOI: 10.1016/j.immuni.2010.08.009
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The Hunt for iNKT Cell Antigens: α-Galactosidase-Deficient Mice to the Rescue?
Journal article published in 2010 by
Luc Van Kaer,
Sebastian Joyce 
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Abstract
The endogenous lipids that control the functions of invariant natural killer T (iNKT) cells remain enigmatic. In this issue of Immunity, Darmoise et al. (2010) report that lysosomal alpha-galactosidase A destroys self-antigens recognized by iNKT cells.