Wiley, Angewandte Chemie International Edition, 17(49), p. 3022-3025, 2010
Wiley, Angewandte Chemie, 17(122), p. 3086-3089, 2010
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(Figure Presented) Si'l vous plait? A facile and general method has been developed to encapsulate polyhistidine-tagged proteins in silica nanoparticles (NPs; gray, see picture) using calcium ions (yellow). The enhanced green fluorescence protein (EGFP) encapsulated in the silica NPs shows a substantial increase in fluorescence intensity and stability against denaturants, protease, and heat.