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Elsevier, Forensic Science International: Genetics, 2(7), p. 290-295, 2013

DOI: 10.1016/j.fsigen.2012.12.002

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Paternity exclusion power: Comparative behaviour of autosomal and X-chromosomal markers in standard and deficient cases with inbreeding

Journal article published in 2013 by Nádia Pinto, Leonor Gusmão, Thore Egeland, António Amorim ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

In paternity testing the informativeness of genetic markers is traditionally measured through the probability of finding, in randomly chosen individuals, inconsistencies with parent to child Mendelian rules of transmission. This statistic, called power of exclusion (PE), paternal exclusion chance or probability, can be defined for duos (mother not typed) or trios (random false fathers are matched against mother/child pairs) and performed both for autosomal and X-chromosomal markers (restricted to paternity testing involving daughters). PE is an a priori statistic, in the sense of not depending on the individual's genetic data of a case, being dependent however on the estimates of genetic markers allele (or haplotype) frequencies.