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American Society for Microbiology, Clinical and Diagnostic Laboratory Immunology, 6(8), p. 1271-1276, 2001

DOI: 10.1128/cdli.8.6.1271-1276.2001

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Analogs of Eap Protein Are Conserved and Prevalent in Clinical Staphylococcus aureus Isolates

Journal article published in 2001 by Muzaffar Hussain, Karsten Becker ORCID, Christof von Eiff, Georg Peters, Mathias Herrmann
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

ABSTRACT Map and Eap are secreted Staphylococcus aureus proteins that interact with various extracellular matrix molecules. PCR analysis using map primers yielded positive reactions in 97.9% of S. aureus isolates but not in Staphylococcus epidermidis isolates. Cloning and sequencing of the conferring genes revealed a high degree of overall homology combined with size variability of the gene product due to various repeat numbers and early translation termination in a poly(A) region. Thus, Map and Eap may provide a potential novel tool for S. aureus identification and typing.