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Elsevier, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, (702), p. 47-49

DOI: 10.1016/j.nima.2012.07.061

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PET/MRI in the infarcted mouse heart with the Cambridge split magnet

Journal article published in 2013 by Guido Buonincontri, Stephen J. Sawiak, Carmen Methner, Thomas Krieg ORCID, Robert C. Hawkes, T. Adrian Carpenter, T. Adrian Carpenter
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Chronic heart failure, as a result of acute myocardial infarction, is a leading cause of death worldwide. Combining diagnostic imaging modalities may aid the direct assessment of experimental treatments targeting heart failure in vivo. Here we present preliminary data using the Cambridge combined 18FDG PET/MRI imaging system in a mouse model of acute myocardial infarction. The split-magnet design can deliver uncompromised MRI and PET performance, for better assessment of disease and treatment in a preclinical environment.