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Elsevier, Journal of Vascular Surgery, 3(49), p. 814, 2009

DOI: 10.1016/j.jvs.2009.01.051

Elsevier, European Journal of Vascular and Endovascular Surgery, 3(37), p. 297-299, 2009

DOI: 10.1016/j.ejvs.2008.11.014

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Search for Serum Biomarkers Associated with Abdominal Aortic Aneurysm Growth – A Pilot Study

Journal article published in 2009 by M. Vega de Céniga, M. Esteban, J. M. Quintana ORCID, A. Barba, L. Estallo, N. de la Fuente, B. Viviens, J. L. Martin-Ventura
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

IntroductionSerological biomarkers could reflect asymptomatic infrarenal aortic aneurysm (AAA) activity and guide patient management.ReportSerum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin and lipoprotein(a) were measured in blood samples from 35 AAA patients and 35 controls and correlated with the aortic diameter and AAA growth in the previous 12 months.We found a positive correlation between CRP and AAA diameter (r = 0.46; p = 0.007) and alpha 1-antitrypsin and AAA growth (r = 0.55; p = 0.004).ConclusionsAlpha 1-antitrypsin may be a promising biomarker of AAA growth.