Published in
Elsevier, Journal of Vascular Surgery, 3(49), p. 814, 2009
DOI: 10.1016/j.jvs.2009.01.051
Elsevier, European Journal of Vascular and Endovascular Surgery, 3(37), p. 297-299, 2009
DOI: 10.1016/j.ejvs.2008.11.014
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Search for Serum Biomarkers Associated with Abdominal Aortic Aneurysm Growth – A Pilot Study
,
A. Barba,
L. Estallo,
N. de la Fuente,
B. Viviens,
J. L. Martin-Ventura
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Abstract
IntroductionSerological biomarkers could reflect asymptomatic infrarenal aortic aneurysm (AAA) activity and guide patient management.ReportSerum concentrations of C-reactive protein (CRP), alpha 1-antitrypsin and lipoprotein(a) were measured in blood samples from 35 AAA patients and 35 controls and correlated with the aortic diameter and AAA growth in the previous 12 months.We found a positive correlation between CRP and AAA diameter (r = 0.46; p = 0.007) and alpha 1-antitrypsin and AAA growth (r = 0.55; p = 0.004).ConclusionsAlpha 1-antitrypsin may be a promising biomarker of AAA growth.