Published in
Elsevier, Journal of Bioscience and Bioengineering, 2(113), p. 258-261
DOI: 10.1016/j.jbiosc.2011.09.025
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Hypergravity effects on myoblast proliferation and differentiation
Journal article published in 2011 by
Gianni Ciofani,
Leonardo Ricotti,
Jacopo Rigosa,
Arianna Menciassi,
Virgilio Mattoli 
,
Monica Monici
,
Monica Monici
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Abstract
This study aimed at the investigation of behavior of myoblasts in conditions of altered gravity. C2C12 cells underwent stimulations by different hypergravity intensities (2 h at 5 g, 10 g, and 20 g) in the Large Diameter Centrifuge of the European Space Agency (ESA), highlighting positive effects on both proliferation and differentiation.