Elsevier, DNA Repair, (30), p. 53-67, 2015
DOI: 10.1016/j.dnarep.2015.03.007
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Fig. 1. Overview of the database's key features. (A) The database's main page (HOME) has a menu that provides links to background information about the database (ARTICLE, METHODS, RESEARCH GROUP) and links to the database's main sections, which are the lists of chromatin remodeling and DNA repair genes (GENE LISTS) and their cell cycle expression profiles (CELL CYCLE). (B) The “GENE LISTS” pages provide links to information about each gene's function and genomic context. Chromatin remodeling and DNA repair genes have separate pages; shown here is an excerpt of the DNA repair genes. Note that some multifunctional genes, such as HELLS or TOP2A, are present on both. (C) The “CELL CYCLE” pages show chromatin remodeling and DNA repair genes with significant cell cycle dependent regulation in at least one of the seven datasets examined. Abbreviated cell cycle phases (G1/S, S, G2, G2/M, and M/G1) show the phase in which a gene has its peak expression. The abbreviations NR and NTR indicate datasets in which the gene was not detected to be transcriptionally or translationally regulated, respectively. Chromatin remodeling and DNA repair genes have separate pages; shown here is an excerpt of the DNA repair genes, which are grouped by DNA repair pathway. Each gene links to a figure (D) that shows the gene's expression profile and the cell cycle phase distribution for the first four experiments listed in the table. (D) The expression profiles of FEN1.