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Elsevier, Diabetes Research and Clinical Practice, 1(104), p. e26-e28, 2014

DOI: 10.1016/j.diabres.2013.12.061

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The relation between glycemic control and HDL-C in type 2 diabetes: a preliminary step forward?

Journal article published in 2014 by Giulia Barbarossa, Alessandra Renzi, Laura D’Erasmo, Antonio Gallo ORCID, E. Grieco, Marco Rossetti, A. Carnovale, M. Santilli, Elisabetta Mandosi, Paola Coletta, Daniela Pergolini, Susanna Morano, Marianna Maranghi
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

Low high-density lipoprotein cholesterol (HDL-C) levels are associated with cardiovascular (CV) disease in type 2 diabetes (T2D). Unfortunately available drugs to increase HDL-C have failed to demonstrate a reduction in CV risk. We assessed the effect of improving glycemic control on HDL-C levels. A 6-month intervention resulted in significant improvement in HbA1c but not in HDL-C levels. However, when considering the subgroup of subjects with low levels of HDL-C at baseline, we found a significant and inverse relation between improvement in HbA1c and HDL-C levels. (C) 2014 Elsevier Ireland Ltd. All rights reserved.