Moulting is a complex process, induced by diet manipulation, which results in renewal of reproductive system and subsequent better production. Conventionally, moulting has been practised by utilising feed withdrawal in many developing countries, however, this has been associated with many drawbacks. Alternative types of moulting practices have been studied, however, these are not practised widely due to a range of undesirable effects. As a consequence of the beneficial effects on laying hens, better post-moult performance and a less criticised method according to poultry welfare advocates, Zn-induced moulting has been considered superior to forced-moulting. Different aspects of Zn-induced moulting related to physiology and production, with special reference to immunohistochemistry of pituitary gland as affected by Zn-induce moulting are included in this review.