Elsevier, Tetrahedron Letters, 21(50), p. 2601-2604
DOI: 10.1016/j.tetlet.2009.03.107
Full text: Unavailable
The treatment of protected Thr peptides with excess polymer-bound IBX effects sequential oxidation of the Thr secondary alcohol to the ketone, followed by hydroxylation of the alpha carbon of the Thr residues with loss of stereochemistry at this position.