A single-center prospective randomized controlled trial evaluating the safety and efficacy of IntraCoronary Erythropoietin delivery BEfore Reperfusion: Gauging infarct size in patients with acute ST-segment elevation myocardial infarction. Study design and rationale of the ‘ICEBERG Trial’11Trial registration: http://www.ClinicalTrials.gov identifier: NCT01538771.