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Cell Press, Cancer Cell, 5(20), p. 551-553, 2011

DOI: 10.1016/j.ccr.2011.10.031

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Collaboration between PcG Proteins and MLL Fusions in Leukemogenesis: An Emerging Paradigm

Journal article published in 2011 by Bernd B. Zeisig, Mari-Francis Arteaga, Cecile Thirant ORCID, Chi Wai Eric So
This paper was not found in any repository, but could be made available legally by the author.
This paper was not found in any repository, but could be made available legally by the author.

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Abstract

PcG and TrxG proteins mostly with opposite transcriptional activities play key roles in normal and malignant development. In this issue of Cancer Cell, Tan et al. report an unexpected collaboration between CBX8 and MLL-AF9 in leukemia, revealing a far more complicated functional crosstalk between these master epigenetic regulators in oncogenesis.