Structural and Thermodynamic Analyses of α‐L‐Fucosidase Inhibitors
Journal article published in 2010 by
Alicia Lammerts van Bueren,
Alicia Lammerts van Bueren,
Shinde D. Popat,
Chun-Hung Lin,
Gideon J. Davies 
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Abstract
(Chemical Equation Presented) What contributes what? The inhibition of an α-L-fucosidase by two imino-sugar inhibitors is studied through the X-ray crystallography of enzyme-inhibitor complexes and thermodynamic dissection of binding over a range of pH values.