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Public Library of Science, PLoS ONE, 4(4), p. e5271, 2009

DOI: 10.1371/journal.pone.0005271

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Impact of Pretreated Switchgrass and Biomass Carbohydrates on Clostridium thermocellum ATCC 27405 Cellulosome Composition: A Quantitative Proteomic Analysis

Journal article published in 2009 by Babu Raman, Chongle Pan, Gregory B. Hurst ORCID, Miguel Rodriguez, Catherine K. McKeown, Patricia K. Lankford, Nagiza F. Samatova, Jonathan R. Mielenz
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Economic feasibility and sustainability of lignocellulosic ethanol production requires the development of robust microorganisms that can efficiently degrade and convert plant biomass to ethanol. The anaerobic thermophilic bacterium Clostridium thermocellum is a candidate microorganism as it is capable of hydrolyzing cellulose and fermenting the hydrolysis products to ethanol and other metabolites. C. thermocellum achieves efficient cellulose hydrolysis using multiprotein extracellular enzymatic complexes, termed cellulosomes.