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Wiley, ChemBioChem, 13(8), p. 1483-1485, 2007
Wiley-VCH Verlag, ChemInform, 46(38), 2007
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Telomerase: A Dimeric Ménage à Trois
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Abstract
Core components of an attractive drug target. Cohen et al. have recently demonstrated that the complex of human active telomerase, an almost universal marker for cancer, involves two copies of each of three components (hTR, hTERT and dyskerin). (Figure Presented)