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Portland Press, Biochemical Journal, 2(180), p. 441-443

DOI: 10.1042/bj1800441

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Control of hepatic triacylglycerol synthesis. Diurnal variations in hepatic phosphatidate phosphohydrolase activity and in the concentrations of circulating insulin and corticosterone in rats.

Journal article published in 1979 by A. M. Knox, R. G. Sturton, J. Cooling, D. N. Brindley
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This paper is available in a repository.

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Abstract

Male rats were kept for 14 days with alternating 12h periods of light and darkness. The hepatic activity of soluble phosphatidate phosphohydrolase and the concentration of serum insulin were maximum at about 2h after dark. The peak concentration of serum corticosterone occurred 2h before the dark period. It is proposed that corticosterone is partly responsible for the increased phosphohydrolase activity, and that this enables the liver to increase its capacity to synthesize triacylglycerols during the period of maximum feeding.