Published in
Elsevier, BBA - General Subjects, 10(1830), p. 4813-4819, 2013
DOI: 10.1016/j.bbagen.2013.06.021
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Honokiol: A non-adipogenic PPARγ agonist from nature☆
Journal article published in 2013 by
Atanas G. Atanasov 
,
Jian N. Wang,
Shi P. Gu,
Jing Bu,
Matthias P. Kramer,
Lisa Baumgartner,
Nanang Fakhrudin,
Angela Ladurner ,
Clemens Malainer,
Anna Vuorinen,
Stefan M. Noha,
Stefan Schwaiger,
Judith M. Rollinger,
Daniela Schuster ,
Hermann Stuppner
and other authors.
,
Jian N. Wang,
Shi P. Gu,
Jing Bu,
Matthias P. Kramer,
Lisa Baumgartner,
Nanang Fakhrudin,
Angela Ladurner ,
Clemens Malainer,
Anna Vuorinen,
Stefan M. Noha,
Stefan Schwaiger,
Judith M. Rollinger,
Daniela Schuster ,
Hermann Stuppner
and other authors.
This paper is available in a repository.
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Abstract
•Honokiol is identified and characterized as novel partial PPARγ agonist from nature.•In cell models honokiol increases glucose uptake but is not adipogenic.•In KKAy diabetic mice it decreases blood glucose and suppresses weight gain.•PPARγ agonism of honokiol may explain the use of Magnolia bark in traditional medicine.