Published in
Elsevier, The American Journal of Pathology, 2(181), p. 376-379, 2012
DOI: 10.1016/j.ajpath.2012.06.006
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A Brief History of Anti-VEGF for the Treatment of Ocular Angiogenesis
Journal article published in 2012 by
Leo A. Kim 
,
Patricia A. D'Amore
,
Patricia A. D'Amore
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Abstract
In 1994, The American Journal of Pathology published a key article reporting that hypoxic retina produces vascular endothelial growth factor (VEGF), suggesting a role for VEGF in ocular neovascularization. Subsequent developments in anti-VEGF treatment for neovascular eye disease have improved visual outcomes and changed the standard of care in retinal medicine and ophthalmology.