Published in
Cell Press, Trends in Biochemical Sciences, 10(26), p. 582-584
DOI: 10.1016/s0968-0004(01)01969-7
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CHASE: an extracellular sensing domain common to transmembrane receptors from prokaryotes, lower eukaryotes and plants
Journal article published in 2001 by
Christophe Mougel,
Igor B. Zhulin 
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Abstract
A novel extracellular ligand-binding domain, termed CHASE, is described in sensory adenylyl and diguanylate cyclases, and histidine kinases, in several bacterial species, Dictyostelium and plants. The CHASE domain is predicted to sense stimuli that are specific for the developmental program of an organism.