Published in
Elsevier, Year Book of Medicine, (2011), p. 96-97
DOI: 10.1016/j.ymed.2011.08.072
Oxford University Press (OUP), Clinical Infectious Diseases, 12(51), p. 1449-1457
DOI: 10.1086/657401
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- [www.ncbi.nlm.nih.gov] | PDF
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- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [europepmc.org] | PDF
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Long-Term Survival of HIV-Infected Children Receiving Antiretroviral Therapy in Thailand: A 5-Year Observational Cohort Study
,
Program for Hiv Prevention and Treatment Study Team,
Gonzague Jourdain,
Rawiwan Hansudewechakul,
Suparat Kanjanavanit,
Suchat Hongsiriwon,
Chaiwat Ngampiyasakul,
Pornchai Technakunakorn,
Somboon Sriminiphant,
Nicole Ngo-Giang-Huong,
Trinh Duong,
Sophie Le Coeur,
Shabbar Jaffar,
Marc Lallemant,
V. Sundareshan
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Abstract
Background.? There are scarce data on the long-term survival of human immunodeficiency virus (HIV)-infected children receiving antiretroviral therapy (ART) in lower-middle income countries beyond 2 years of follow-up. Methods.? Previously untreated children who initiated ART on meeting immunological and/or clinical criteria were followed in a prospective cohort in Thailand. The probability of survival up to 5 years from initiation was estimated using Kaplan-Meier methods, and factors associated with mortality were assessed using Cox regression analyses. Results.? Five hundred seventy-eight children received ART; of these, 111 (19.2%) were followed since birth. At start of ART (baseline), the median age was 6.7 years, 128 children (22%) were aged