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National Institute of Environmental Health Sciences (NIEHS), Environmental Health Perspectives, 4(121), p. 459-466, 2013

DOI: 10.1289/ehp.1205951

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Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes

This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Background: Endocrine-disrupting chemicals (EDCs) influence the activity of estrogen receptors (ERs) and alter the function of the endocrine system. However, the diversity of EDC effects and mechanisms of action are poorly understood.