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Oxford University Press, Clinical Kidney Journal, 3(5), p. 229-231, 2012

DOI: 10.1093/ckj/sfs021

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Anti-neutrophil cytoplasmic antibody vasculitis presenting with bilateral renal vein thrombosis

Journal article published in 2012 by Christina Wlodek ORCID, Michael Gregory Robson
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

We report a case of anti-neutrophil cytoplasmic antibody (ANCA)-associated necrotizing crescentic glomerulonephritis presenting with bilateral renal vein thrombosis and pulmonary emboli in a patient who also had a lupus anticoagulant and anti-cardiolipin antibodies. Although the link between venous thrombosis and ANCA vasculitis is well established, the coexistence of renal vein thrombosis is unusual. Furthermore, despite the positive ANCA, he was initially negative for antibodies to myeloperoxidase (MPO) and proteinase-3 (PR3), illustrating that a positive ANCA may be significant despite a negative test for antibodies to MPO and PR3.