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F1000 Bio Rep, (1)

DOI: 10.3410/b1-65

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Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers

Journal article published in 2009 by Anna K. Townley, David J. Stephens ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

The basic mechanisms underlying the formation of coated vesicles are now defined in considerable detail. This article highlights recent developments in our understanding of the problem of exporting large macromolecular cargo such as procollagen from the endoplasmic reticulum and discusses the implications that this has for cell and tissue organisation and human disease.