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Preclinical Development Handbook, p. 1167-1227

DOI: 10.1002/9780470249031.ch35

Preclinical Development Handbook, p. 775-827

DOI: 10.1002/9780470249031.ch22

Drug Discovery, Development, and Manufacturing

DOI: 10.1002/9780470571224.pse065

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Physiologically Based Pharmacokinetic Modeling

Journal article published in 2007 by Harvey J. Clewell, Jane R. Kenny, Dermot F. McGinnity, Micaela B. Reddy, Robert J. Riley, Ken Grime, Thierry Lave, Melvin E. Andersen
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

IntroductionPBPK Modeling FundamentalsPBPK Model ImplementationGeneric PBPK ModelsIntegrating Preclinical Data Using the PBPK ModelExamples of the Use of PBPK Modeling in Drug DevelopmentConclusions and Future PerspectivesAcknowledgmentsReferences