Published in
Wiley, Journal of Medical Virology, S1(70), p. S48-S50, 2003
DOI: 10.1002/jmv.10320
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IL-10 gene polymorphism and herpesvirus infections
Journal article published in 2003 by
M. Hurme 
,
M. Haanp��,
T. Nurmikko,
X.-Y. Wang,
M. Virta,
T. Pessi,
S. Kilpinen,
J. Hulkkonen,
M. Helminen
,
M. Haanp��,
T. Nurmikko,
X.-Y. Wang,
M. Virta,
T. Pessi,
S. Kilpinen,
J. Hulkkonen,
M. Helminen
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Abstract
Genetics has an important role in resistance to various infections and it also may modify the clinical picture of an infectious disease. Here, we briefly review our recent data demonstrating that the polymorphism of the IL-10 gene is associated with resistance to some common herpesviruses and, additionally, that this same gene is involved in the regulation of the severity of the infection and in the reactivation process.