The centrosymmetric title complex, [Cu₂Br₄(C₁₁H₁₀N₂O₂)₂]·2H₂O, was one of three complexes isolated by slow evaporation of an acetonitrile reaction mixture of CuBr₂ with di-2-pyridyl ketone (1:1 molar ratio). The title complex contains a 1:1 metal-to-ligand ratio of copper(II) with the hydrated form of the ligand di-2-pyridylmethanediol. The copper centers are bridged by bromide donors, leading to a Cu—Cu distance of 4.090 (6) Å. The crystals form as non-merohedral twins with two components related by a 180° rotation around the normal to [100]; the selected sample had a twin ratio of 0.63:0.37.