Royal Society of Chemistry, RSC Advances, 10(5), p. 7789-7793
DOI: 10.1039/c4ra14405h
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An excited state intramolecular proton transfer (ESIPT) fluorogen, due to its easy hydrogen bonding and AIE characteristics, has demonstrated a fast and selective light-up of the cytoplasm of HeLa cells within 20 seconds. Moreover, the low-cost material preparation, fair cytocompatibility, good photostability and wide pH application range all indicate its great potentials for commercialization.