Published in
Public Library of Science, PLoS Medicine, 11(9), p. e1001338, 2012
DOI: 10.1371/journal.pmed.1001338
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Liver Dysfunction and Phosphatidylinositol-3-Kinase Signalling in Early Sepsis: Experimental Studies in Rodent Models of Peritonitis
Journal article published in 2012 by
Falk A. Gonnert,
Peter Recknagel,
Sandro Lambeck,
Martin Westermann,
Amelie Lupp,
Alex Dyson,
Alain Rudiger 
,
Jane E. Carré,
Andreas Kortgen,
Christoph Krafft ,
Jürgen Popp,
Christoph Sponholz,
Valentin Fuhrmann,
Ingrid Hilger,
Ralf A. Claus
and other authors.
,
Jane E. Carré,
Andreas Kortgen,
Christoph Krafft ,
Jürgen Popp,
Christoph Sponholz,
Valentin Fuhrmann,
Ingrid Hilger,
Ralf A. Claus
and other authors.
This paper is made freely available by the publisher.
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Abstract
Experimental studies in a rat model of fecal peritonitis conducted by Michael Bauer and colleagues show that in this model, changes in liver function occur early in the development of sepsis, with potential implications for prognosis and development of new therapeutic approaches.