A new chlorine-containing sesquiterpene lactone from Achillea ligustica
Journal article published in 2008 by
M.-E. F. Hegazy 
,
Mohamed-Elamir F. Hegazya,
M. E. F.,
Abou El-Hamd H. Mohamed,
Magdi A. El-Sayed,
M. A.,
Shinji Ohta
,
Mohamed-Elamir F. Hegazya,
M. E. F.,
Abou El-Hamd H. Mohamed,
Magdi A. El-Sayed,
M. A.,
Shinji Ohta
This paper is made freely available by the publisher.
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Abstract
Chromatographic investigation of the methylene chloride/methanol extract of the aerial parts of Achillea ligustica afforded a new chlorine-containing sesquiterpene lactone as well as two known compounds. The structures of the compounds were determined by comprehensive NMR studies, including DEPT, COSY, NOE, HMQC, HMBC and HRMS. The neurotrophic activity of the new compound has been measured.