We hypothesized that the availability of a transcatheter aortic valve implantation (TAVI) program in hospitals impacts the overall management of patients with aortic valve disease and hence may also improve post procedural outcomes of conventional surgical aortic valve replacement (SAVR). The aim of the current study was to compare the in-hospital outcomes of SAVR in centers with versus without availability of a TAVI program in an unrestricted large nationwide patient population > 50 years of age. SAVRs performed on patients >50 years of age were identified from the Nationwide Inpatient Sample (NIS) for the years 2011 and 2012 using the ICD-9-CM procedure codes. SAVR cases were divided into two categories: those performed at hospitals with a TAVI program (SAVR-TAVI) and those without (SAVR-non-TAVI). A total of 9,674 SAVR procedures were identified: 4526 (46.79 %) in the SAVR-TAVI group and 5148 (53.21 %) in SAVR-non-TAVI group. The mean age of the study population was 70.2± 0.1 years with majority (53%) of the patients >70 years of age. The mean Carlson’s comorbidity score for patients in SAVR-TAVI group was higher (higher percentage of patients were >80 years of age, had hypertension, congestive heart failure, renal failure and peripheral arterial disease than that of patients in SAVR-non-TAVI group (1.6 vs 1.4, p<0.001). The propensity score matching analysis showed a statistically significant lower in-hospital mortality (1.25% vs. 1.72%, p=0.001) and complications rate (35.6% vs. 37.3%, p=0.004) in SAVR-TAVI group when compared to SAVR-non-TAVI group. The mean length of hospital stay was similar in the two groups the cost of hospitalization was higher in the SAVR-TAVI group ($43,894±483 vs. $41,032±473, p<0.0001). Having a TAVI program was a significant predictor of reduced mortality and complications rate after SAVR in multivariate analysis. In conclusion, this largest direct comparative analysis demonstrates that SAVRs performed in centers with a TAVI program are associated with significantly lower mortality and complications rates when compared to those performed in centers without a TAVI program.