CSIRO Publishing, Australian Journal of Chemistry, 6(59), p. 355, 2006
DOI: 10.1071/ch06136
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From direct atom manipulation and nano-fabrication, to single molecule sensing and probing energy landscapes, the tools of the nanotech age are here. Scanned probe microscopies (SPM) offer opportunities to directly interact with matter in native environments and their evolution shows no signs of slowing. How might this toolkit adapt for new and outstanding problems in science? Here some directions are entertained and potential developments explored.