Cell Press, Current Biology, 10(13), p. R385-R387, 2003
DOI: 10.1016/s0960-9822(03)00316-6
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Chromosome segregation depends on proper orientation of sister kinetochores. The protein Csm1 is required for mono-orientation of sister kinetochores at meiosis I in budding yeast. Surprisingly, its homologue in fission yeast appears instead of clamp micro-tubule binding sites together on single mitotic kinetochores so that they all face one spindle pole.