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Springer Verlag, European Journal of Nuclear Medicine and Molecular Imaging, 11(41), p. 2042-2050

DOI: 10.1007/s00259-014-2818-3

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Prognostic value of tumour blood flow, [18F]EF5 and [18F]FDG PET/CT imaging in patients with head and neck cancer treated with radiochemotherapy

Journal article published in 2014 by Gaber Komar, Kaisa Lehtiö, Marko Seppänen, Olli Eskola, Helena Levola, Paula Lindholm, Hannu Sipilä, Jan Seppälä ORCID, Reidar Grénman, Olof Solin, Heikki Minn ORCID
This paper is available in a repository.
This paper is available in a repository.

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Abstract

Purpose: In order to improve the treatment of squamous cell carcinoma of the head and neck, precise information on the treated tumour’s biology is required and the prognostic importance of different biological parameters needs to be determined. The aim of our study was to determine the predictive value of pretreatment PET/CT imaging using [18F]FDG, a new hypoxia tracer [18F]EF5 and the perfusion tracer [15O]H2O in patients with squamous cell cancer of the head and neck treated with radiochemotherapy.