Springer Verlag, European Journal of Nuclear Medicine and Molecular Imaging, 11(41), p. 2042-2050
DOI: 10.1007/s00259-014-2818-3
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Purpose: In order to improve the treatment of squamous cell carcinoma of the head and neck, precise information on the treated tumour’s biology is required and the prognostic importance of different biological parameters needs to be determined. The aim of our study was to determine the predictive value of pretreatment PET/CT imaging using [18F]FDG, a new hypoxia tracer [18F]EF5 and the perfusion tracer [15O]H2O in patients with squamous cell cancer of the head and neck treated with radiochemotherapy.