This paper elaborates on the design implementation and performance evaluation of a prototype Radio Resource Management (RRM) framework for TV white spaces (TVWS) exploitation, under the Real Time Secondary Spectrum Market (RTSSM) policy. The proposed RRM is applied in centralised CR network architectures, where exploitation of the available TVWS is orchestrated by a Spectrum Broker. Efficient RRM performance as a matter of maximum-possible spectrum utilisation and minimum fragmentation is performed by decision making optimisation methods based on the Backtracking and the Simulated Annealing algorithms. Experimental tests that were carried-out under controlled conditions environment, verified the validity of the proposed framework, besides identifying fields for further research.