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Thieme Gruppe, Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry, 20(2006), p. 3423-3426, 2006

DOI: 10.1055/s-2006-956483

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Beneficial effect of Mukaiyama reagent on macrobislactamization reactions

Journal article published in 2006 by Lucie Vandromme, Marie-Paule Teulade-Fichou, David Monchaud
This paper is available in a repository.
This paper is available in a repository.

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Abstract

An expeditious two-step procedure was developed to accede to new tetraamide macrocycles. The key step of this diversity-oriented procedure is a highly efficient Mukaiyama salt promoted macrobislactamization. Preliminary mechanistic investigations are also reported.