Published in
Public Library of Science, PLoS Biology, 3(8), p. e1000605, 2011
DOI: 10.1371/journal.pbio.1000605
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- Public Library of Science
- [www.ncbi.nlm.nih.gov] | PDF
- [dspace.mit.edu] | PDF
- [europepmc.org] | PDF
- [www.researchgate.net] | PDF
- [citeseerx.ist.psu.edu] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
- [www.ncbi.nlm.nih.gov] | PDF
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Enzymatic Blockade of the Ubiquitin-Proteasome Pathway
Journal article published in 2011 by
Robert Ernst,
Jasper H. L. Claessen,
Britta Mueller,
Sumana Sanyal,
Eric Spooner,
Annemarthe G. van der Veen 
,
Oktay Kirak,
Christian D. Schlieker,
Wilhelm A. Weihofen,
Hidde L. Ploegh
,
Oktay Kirak,
Christian D. Schlieker,
Wilhelm A. Weihofen,
Hidde L. Ploegh
This paper is made freely available by the publisher.
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Abstract
A viral ubiquitin-specific protease domain blocks cellular protein turnover by preemptive removal of ubiquitin chains and establishes an essential role for deubiquitylation in the removal of unfolded proteins from the endoplasmic reticulum.