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American Society of Tropical Medicine and Hygiene, American Journal of Tropical Medicine and Hygiene, 3(92), p. 477-478, 2015

DOI: 10.4269/ajtmh.14-0484

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Demonstration that a Case of Human Alveolar Echinococcosis in Minnesota in 1977 was Caused by the N2 Strain.

Journal article published in 2015 by Claudia Klein, Alessandro Massolo ORCID
This paper is made freely available by the publisher.
This paper is made freely available by the publisher.

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Abstract

Alveolar echinococcosis is the most serious helminthic zoonosis of the northern hemisphere affecting humans. The causative agent, Echinococcus multilocularis, occurs in geographically distinct strains that can be distinguished based on sequence variations of mitochondrial genes and nuclear microsatellite targets. This report finds that the human case of Alveolar echinococcosis occurring in Minnesota in 1977 was caused by the N2 haplotype described previously; the N2 haplotype is distinct from European and Asian isolates of the parasite and is restricted to the central region of North America.