Published in
Cell Press, Molecular Cell, 6(56), p. 719-720, 2014
DOI: 10.1016/j.molcel.2014.12.010
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Resemble and Inhibit: When RLR Meets TGF-β
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Abstract
In this issue, Xu etal. (2014) show that innate antiviral RIG-I-like receptors (RLR) signaling represses TGF-β-induced growth inhibition, epithelial-mesenchyme transition (EMT), and regulatory Tcell (Treg) differentiation via IRF3-mediated Smads function. In this issue, Xu etal. (2014) show that innate antiviral RIG-I-like receptors (RLR) signaling represses TGF-β-induced growth inhibition, epithelial-mesenchyme transition (EMT), and regulatory Tcell (Treg) differentiation via IRF3-mediated Smads function.