Participation of endogenous corticosteroids in inflammatory response in type 2 streptozotocin diabetic rats
Journal article published in 2004 by
G. A. N. de Melo,
J. L. Sartoretto,
S. M. Caparroz Assef,
C. A. Bersani Amado,
Z. B. Fortes,
R. K. N. Cuman 
Abstract
The inflammatory response is decreased in diabetic animals. After adrenals removal this impaired response in type 2 diabetic rats evaluated by pleurisy and vascular permeability tests was restored. Our studies demonstrate that endogenous corticosteroids play a partial role in the impaired inflammatory response in type 2 streptozotocin diabetic rats.